In her graduate work, Chantal was working on developing a surface modification technique to optimize and functionalize nanoparticles (NPs) designed by inverse emulsion polymerization for high drug loading efficiency. A drug-coated balloon prototype was developed that successfully delivered NPs carrying an anti-restenosis drug to arterial tissue in vivo that showed enhanced vessel transfer and retention compared to delivery of the drug alone.
She has been incredibly successful throughout her studies, with her work being the subject of a US Provisional Patent, and, a first authored publication from the lab on the advancements of nanotechnology in the treatment of restenosis, in the American Heart Association’s ‘Atherosclerosis, Thrombosis, and Vascular Biology’ (May 2023).
Chantal is now producing two additional manuscripts based on her thesis work, as well as assisting CDMO Hovione with microparticle research using microfluidic techniques through a collaboration with UofT.